# Methodology — MBI

## Design
Systematic literature review (2010-2025).

## Inclusion criteria
- RCTs with control group
- Adults (≥18 years) in Latin American settings
- Minimum 4-week intervention

## Outcome measures
- Hamilton Anxiety Scale (HAM-A)
- STAI (State-Trait Anxiety Inventory)
- Neuropsychological tests for memory and attention
